Niclobest 500 Mg

Introduction to Niclosamide 500 mg

Niclobest 500 mg is an anthelminthic, taken orally in the form of pills. Infection caused by parasites is treated with niclosamide. Parasites, particularly Beef worms and fish tapeworms, etc., infections are cured with Niclobest 500. Future clinical research has shown its benefit in cancer treatment. However, it is seen in clinical trials that it cannot work against other worms like roundworms and flukes.

Other species like Schistosoma sp. infections, liver abscesses, hepatic amoebiasis, periodontitis, diarrhea, intestinal amoebiasis, filariasis, and others have also been treated with niclosamide.

It kills parasites by killing them and is passed in the stool. It can be seen in the stool, and if not seen, it may have been destroyed in the intestine.

What is the mechanism of action of niclosamide?

Niclosamide works by killing tapeworms by acting on their metabolic and reproductive pathways. Niclosamide acts on the pathway responsible for the formation of ATP (a source of energy), specifically, it acts to uncouple oxidative phosphorylation. Due to a decrease in energy, the death of parasites occurs.

Death parasite is passed in the stool or sometimes destroyed in the intestine cannot be seen in the stool. Niclobest 500mg also disrupts the life cycle of the parasite by damaging its DNA.

Breast cancer is an emerging cancer among women. It has been reported that Wnt/β-catenin is inhibited by Niclobest 500, which is the main pathway for promoting cancer cells present in the Breast. Various pathways responsible for the reproduction of cancer cells are being inhibited by niclosamide. NF-KB factor transcription is responsible for the multiplication of tumor cells, i.e., promoting tumorigenesis; Niclobest 500 tablet is also responsible for the inhibition of this pathway. In this way, Niclosamide acts on cancerous cells by inhibiting pathways that promote the growth of cancer cells.

What is niclosamide used for?

It is used in the treatment of Taeniasis Infection caused by the pork tapeworms (Taenia solium) and the beef tapeworms (Taenia saginata).

It is a great medicine for parasite treatment and has shown an effective result as a cancer medicine too.

Other Available Medicine:

• Mebendazole 100
• Mebendazole 500

Side effect:

• Abdominal or stomach cramps or pain
• Diarrhea
• Loss of appetite
• Nausea or vomiting
• Dizziness or lightheadedness
• Drowsiness
• Itching of the rectal area
• Skin rash
• Unpleasant taste

Drug Interaction

List of drugs that interact with Niclosamide:

• Acetyl sulfisoxazole
• Acyclovir
• Fezolinetant
• Ropinirole
• Roflumilast topical
• Melatonin

Precautions and Warnings

• One should undergo liver function tests regularly.
• Allergic reactions are common while taking Niclobest 500mg.

Storage

• Avoid direct contact with the sun.
• Keep it in a dry place.
• Keep away from the reach of a child.

FAQ

1. What is niclosamide used for?

Ans: Niclosamide is used to treat parasitic infections.

2. Is niclosamide safe during pregnancy?

Ans: Its safety during pregnancy has not been established; consult your doctor.

3. Can I drink alcohol while taking niclosamide?

Ans: It is best to avoid alcohol, as it may increase the risk of side effects.

4. How does niclosamide work?

Ans: It disrupts the energy production in tapeworms, leading to their death.

5. What are the side effects of niclosamide?

Ans: Side effects of niclosamide cause vomiting and itchiness.