Wormentel 222 (Fenbendazole 222 mg)

Introduction of Fenbendazole

Fenbendazole, a Benzimidazole, presents a wide-spectrum anthelmintic effect. Wormentel 222 mg is an animal-grade medicine used for treating parasitic infections in animals, effective against several gastrointestinal parasites, including Giardia, roundworms, hookworms, whipworms, the Taenia genus of tapeworms, pinworms, Aelurostrongylus, paragonimiasis, strongyles, and Strongyloidiasis.

Fenbendazole 222 mg is approved for administering under veterinary care to sheep, cattle, horses, fish, dogs, cats, rabbits, and seals. It can cross the blood-brain barrier, which is why it is considered a good active compound for treating parasitic infections.

Clinical trials are been performed on Fenbendazole to determine its anti-cancer properties, which can be used as a great anti-cancer medicine due to its high safety profile, accessibility, and unique anti-proliferative activities. Fenbendazole 222 mg is the preferred benzimidazole compound to treat cancer in humans.

It can be said that, along with anti-parasitic properties, it can also be effective as an anti-cancer medicine in humans.

Mechanism of work

It binds with the β-tubulin within the microtubules of the parasite and inhibits their formation, resulting in disruption of cell division, followed by inhibition of glucose uptake and transport, leading to a shortage of energy, which is obtained by ATP (Adenosine Triphosphate) released in this process, resulting in paralyzing the parasite until it dies.

What is Wormentel 222 mg used for?

Worm infections, schistosome infections, diarrhea, periodontitis, liver abscesses, intestinal amoebiasis, hepatic amoebiasis, and filariasis.

While fenbendazole was initially formulated for veterinary use, preliminary research suggests that Wormentel 222 mg may inhibit cancer cell growth and induce cancer cell death through various mechanisms, such as disruption of microtubule formation and inhibition of glucose uptake.

Chemotherapy uses medications to destroy cancer cells or hinder their growth. It can be administered before or after surgery or as the primary treatment for advanced or metastatic pancreatic cancer.

Roundworms, hookworms, whipworms, the Taenia genus of tapeworms, pinworms, Aelurostrongylus, paragonimiasis, and strongyles.

Treats neurocysticercosis, an infection of the nervous system caused by pork tapeworms. May be effective in cancer treatment.

How to take Wormentel 222?

Swallow it whole with a full glass of water. Do not crush, chew, or break the tablet. It should be taken with food.

It should not be taken by pregnant women. Suspected of damaging fertility.

Other Strength:

• Fenbendazole 444
• Fenbendazole 500
• Fenbendazole 150

Side effects 

• Nausea
• Vomiting
• Headache
• Abdominal pain
• Dizziness
• Vertigo
• Abnormal liver function tests
• Fever
• Hair loss

Drug Interaction

Drug interactions may occur if salicylanilides such as dibromsalan and niclosamide are co-administered. Abortions in cattle and deaths in sheep have been reported after using these medications together.

Abortions in domestic ruminants have been associated with the concurrent use of anti-trematode therapeutic agents.

Wormentel 222mg is poorly absorbed from the gastrointestinal tract in most species.

The drug that might have caused the bone marrow aplasia was not determined. A similar drug combination was given to a healthy animal, but no anemia developed.

Precautions and Warnings

• Monitor your blood counts and liver function before you start taking Wormentel 222 mg medicine and regularly throughout your treatment.
• Allergic reaction (anaphylaxis) including hives, facial swelling, lethargy, trouble breathing, or collapse in animals.
• Avoid being near people who are sick or have infections. Inform your doctor if you develop signs of infection. There can be potential hepatotoxicity in a few patients.
• Do not skip doses and finish the prescribed course, even if you start to feel better. Stopping it early may increase your risk of further infection.
• It should not be taken during pregnancy. It can be harmful to an unborn baby.

Storage

Keep away from children below the age of five.

FAQs

1. How quickly does fenbendazole start working?

Ans: Fenbendazole is available from your veterinarian in tablet form, and it will start treating the parasites in 1 to 2 days.

2. What are the negative side effects of fenbendazole?

Ans: Adverse effects of Wormentel 222 are very rare but can include decreased appetite, vomiting, diarrhea, and rarely reversible pancytopenia.

3. What is the benefit of fenbendazole tablets?

Ans: To treat ringworm, other helminths, and a variety of parasitic infections in laboratory animals, livestock, companion animals, and people.

4. Does fenbendazole cause weight gain?

Ans: Deworming with Wormentel 222 increased weight gains by approximately 22.0 and 15.4 pounds, respectively, over the entire period.

5. How does fenbendazole affect humans?

Ans: Effects on a human small cell lung carcinoma cell line.